Prep HPLC Column, RP C4, 10um, 100A. 30mm ID x 50mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The moderate hydrophobicity of the C4 ligand makes this stationary phase an excellent choice for purification of hydrophobic and neutral compounds while providing lower retention than C18 phases and greater retention than many C8 phases. The fully endcapped surface delivers dependable chromatographic performance and reproducible purification results.

68004-P30-50 is a preparative HPLC column with dimensions of 30 mm ID x 50 mm length, packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The large internal diameter is designed for substantial sample loading and efficient fraction collection, while the short 50 mm length is optimized for rapid purification cycles, method scouting, and process development. Typical flow rates are approximately 30–80 mL/min depending on mobile phase conditions, system capabilities, and sample requirements.

This column is intended for preparative HPLC purification where target compounds are isolated and collected for further research, development, formulation, or production. The short bed length is particularly useful when throughput and cycle time are prioritized over maximum chromatographic resolution. Applications include pharmaceutical research, synthetic chemistry, natural product purification, reference standard preparation, and process optimization. A specialized preparative HPLC system capable of high flow rates, large injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • RP C4 Butyl stationary phase

  • Fully double endcapped chemistry

  • Traditional butyl (C4) bonded phase

  • Designed for preparative HPLC purification

  • High sample loading capacity

  • 10 µm particles for lower operating backpressure

  • Suitable for high flow rates

  • Less retention than C18 columns

  • Fast purification cycles with 50 mm column length

  • Excellent for process development and method scouting

Typical Applications

  • Preparative HPLC purification

  • Small molecule isolation

  • Pharmaceutical research

  • Synthetic chemistry

  • Natural product purification

  • Reference standard preparation

  • Process optimization

  • Method development

  • Pilot-scale purification

  • Fraction collection

Specifications

  • Product Type: Preparative HPLC Column

  • Stationary Phase: RP C4 Butyl

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Butyl (C4)

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 100 Å

  • Column Dimensions: 30 mm ID x 50 mm

  • Length: 50 mm

  • Typical Flow Rate: 30–80 mL/min

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Designed for purification rather than routine analytical HPLC

  • Used for isolation and collection of purified compounds

  • Offers substantially higher sample loading capacity than analytical columns

  • Requires a preparative HPLC system capable of high flow rates and fraction collection

  • Provides less retention than C18 phases and greater retention than many C8 phases

  • Short column length supports rapid purification and method development workflows

  • Special Order Item


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